Cell-First Longevity Science

From Cells to Surface 

Collagen Cell Renewal is a next-generation, cell-first formula that targets the root causes of aging: collagen breakdown, cellular fatigue, oxidative stress, and declining NAD+ levels.

Every dose features 11 clinically studied ingredients at research-backed levels to deliver functional and visible results. 

The Power of Cellular Health 

Healthy, energized cells are the foundation of healthy skin, steady energy, and long-term vitality. Every function in your body — from collagen production and hydration to energy and cellular repair — starts at the cellular level.

Every day, your cells work to repair damage, produce energy, and maintain healthy collagen — but over time, these processes naturally slow. This shows up on the surface as fine lines and collagen loss, while beneath the surface, it affects energy, clarity, and resilience. One key reason is declining levels of NAD⁺ (nicotinamide adenine dinucleotide), a vital coenzyme that powers mitochondrial energy and supports cellular repair. Without enough NAD⁺, cells struggle to regenerate, leading to visible signs of aging and decreased vitality.

Why Do NAD+ and Collagen Matter?

The Drop in NAD+

NAD+ is one of the most important molecules in the body, fueling over 500 cellular reactions, including DNA repair, metabolism, and mitochondrial energy. Unfortunately, NAD+ levels can fall by as much as 50% by middle age. This decline leads to fatigue, slower repair, and visible signs of aging.

Collagen Cell Renewal works at the intersection of these two critical pathways by restoring collagen structure and replenishing NAD+ for whole-body vitality.

Adapted from Zhu et al., 2015; Chini et al., 2017; Massudi et al., 2012; Lautrup et al., 2019

The Decline of Collagen

By your mid-20s, collagen, the structural protein that keeps skin firm and plump, begins to decline by about 1% each year. By age 60, most people have lost more than half of their natural collagen. This loss contributes to wrinkles, sagging skin, and joint discomfort.

Adapted from Varani et al., 2006; Brincat et al., 1987; Zague, 2008; Krutmann et al., 2017

Backed by Science

Every ingredient in Collagen Cell Renewal is included at research-backed levels. Explore the science behind each group of ingredients:

Dual Collagen Matrix + Vitamin C + Glycine

Stronger, smoother, more resilient skin

Marine and Bovine Collagen Peptides (Type I & III)

Dermal Density | Elasticity | Firmness
Hydrolyzed for superior absorption, these peptides help restore skin elasticity, boost hydration, and support bone and joint health. In a 12-week placebo-controlled clinical trial, collagen supplementation reduced wrinkles by 35% and improved skin elasticity, radiance, and overall appearance (Evans et al., 2020).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Vitamin C

Collagen Synthesis | Enzyme Co-factor| Antioxidan
Often called the ultimate skin defender, vitamin C helps your body build and stabilize collagen for firm, youthful skin. Oral supplementation has been shown to raise skin vitamin C levels and strengthen the skin’s natural defense against UV and pollution-related damage. (Pullar et al., 2017).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Glycine

Collagen Synthesis | Repair
Known as a “collagen multiplier,” glycine boosts fibroblast activity to enhance collagen production, strengthen skin, and accelerate repair. In human skin cell studies, glycine and its derivative glycinamide increased type I and III collagen, and when paired with vitamin C, boosted collagen production by over 150%, highlighting powerful synergy for skin renewal and resilience. (Lee et al., 2022). It also acts as a calming amino acid that supports deeper, more restful sleep (Bannai et al., 2012).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

NAD+ Amplifiers

Recharged cells and youthful energy

Nicotinamide Riboside (NR)

NAD+ Generator | Mitochondrial Energy | Cellular Repair
An advanced form of Vitamin B3 that helps replenish declining NAD⁺ levels to restore cellular energy, support mitochondrial function, and promote DNA repair. Human studies show NR supplementation can raise NAD⁺ by up to 60 percent within just 2 to 3 weeks, helping power healthy aging and cellular vitality (Trammell et al., 2016).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Trimethylglycine (TMG)

NAD+ Methylator | DNA Repair
Also known as betaine, TMG is a natural nutrient that provides essential methyl groups to keep repair and recycling pathways working efficiently. By supporting NAD⁺ recycling and lowering homocysteine, TMG promotes cardiovascular and neurological health. Clinical studies have shown that TMG supplementation can reduce homocysteine levels by 10 to 20 percent (Craig, 2004).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Longevity Antioxidants

Protect your cells and your glow

Resveratrol

Longevity Antioxidant | Sirtuin Activato
Often called a longevity antioxidant, resveratrol helps activate the SIRT1 healthy aging pathway, supports DNA repair, and calms inflammation. Research shows it improves how cells produce energy and protects them from oxidative stress. In animal studies, resveratrol supported health and survival in mice fed a high-fat diet, and human trials have linked it to improvements in metabolic and vascular health (Baur et al., 2006).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

CoQ10

Mitochondrial Energy | ATP Synthesi
Essential for energy and antioxidant defense, CoQ10 powers mitochondrial function while protecting skin from oxidative stress. In a 12-week placebo-controlled clinical trial, supplementation significantly reduced wrinkles and improved skin smoothness, with additional benefits observed for firmness and elasticity (Žmitek et al., 2017).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Hydration and Repair

Plump, hydrated, and calm from within

Hyaluronic Acid (HA)

Hydration | Elasticity
Known as nature’s moisture magnet, HA can bind up to 1,000 times its weight in water, helping skin stay plump, hydrated, and smooth. In a 12-week placebo-controlled clinical trial, oral HA significantly reduced wrinkle depth and improved skin smoothness and suppleness (Hsu et al., 2017).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

Centella Asiatica

Healing | Barrier Suppor
A medicinal plant prized for its calming and restorative properties. In a 6-week clinical trial, an oral supplement containing Centella asiatica extract improved skin elasticity and the visible appearance of stretch marks, supporting its role in skin repair and overall resilience (Park, 2021).

Clinical Studies

Definition: A structural protein comprising about 30% of the body’s protein and 70-80% of connective tissues, forming the scaffolding for skin, bones, and connective tissues.

Provides the essential amino acids that serve as the building blocks for new collagen synthesis—supporting fibroblast activity, dermal matrix repair, and structural protein regeneration.

bomi 365's collagen peptides are sourced from wild caught marine and grass fed bovine and undergo enzymatic hydrolysis to break down its triple-helical structure into bioactive peptides with a low molecular weight—resulting in high bioavailability.

Mechanism of Action: Once ingested, hydrolyzed collagen breaks down into small peptides and amino acids like glycine and proline. It is absorbed in the gut, circulates through the bloodstream, and activates cells in the skin, joints, and bones, promoting tissue repair and synthesis.

Skin: Collagen peptides shown to enhance skin elasticity (6–12 weeks), reduce wrinkles (12 weeks), improve dermal density and firmness (6 months).

General Anti-Aging: Collagen peptides shown to reduce joint pain (12–24 weeks) and improve bone density (12+ months).

Typical Dosage Range Across Studies: 1g - 10g per day

Clinical Study References

DOI: 10.1111/ijd.15518 DOI: 10.3390/jcm13185370 DOI: 10.3390/molecules26164880

DOI: 10.1007/s13555-024-01184-2 DOI: 10.3390/cosmetics11040137

DOI: 10.1007/s13555-024-01251-8 DOI: 10.1111/jocd.13676 DOI: 10.1016/j.amjmed.2025.04.034

DOI: 10.3390/nu10070826 DOI: 10.1177/19476035231221211 DOI: 10.1089/jmf.2015.0022

DOI: 10.1185/030079908X291967 DOI: 10.1155/2024/8752787

The takeaway: Collagen Cell Renewal is not just a collagen supplement. It is a multi-pathway formula, clinically designed to support cellular repair, rebuild skin, restore energy, defend against oxidative stress, and deeply hydrate from within.

Why Choose Collagen Cell Renewal?

Unlike typical collagen formulas that stop at skin-deep benefits, Collagen Cell Renewal is multi-targeted and engineered for superior absorption and broad biological impact. It is a clinically designed formula that works from the inside out to support visible beauty and whole-body vitality.

Benefits You Can See and Feel

  • Boosts collagen production and hydration for smoother, firmer skin
  • Supports cellular repair, DNA protection, and energy production
  • Enhances clarity, focus, and sleep quality
  • Protects against oxidative stress and inflammation
  • Promotes long-term skin vitality and overall wellness

What Sets it Apart

  • Dual-source collagen for a complete skin and joint matrix
  • NAD+ amplification with NR and TMG
  • Antioxidant defense with Resveratrol and CoQ10
  • Clean, refreshing flavor with no fillers or artificial sweeteners
  • Third-party tested for purity, potency, and safety

The Future of Healthy Aging

Radiant skin is just the beginning. Collagen Cell Renewal is your daily ritual for cellular vitality, mental clarity, and graceful longevity. Because true beauty starts where health begins, inside every cell.

Honest Answers

Questions, answered.

  • What makes this different from regular collagen?

    Most collagen products are a single hydrolyzed protein — they give your body the raw material but ignore whether your cells can actually use it. Bomi365 includes 11 ingredients chosen to support the entire production process: NAD+ precursors and CoQ10 for cellular energy, glycine and vitamin C for collagen synthesis, hyaluronic acid for hydration, and resveratrol to protect new collagen from oxidative breakdown.

  • How long until I see results?

    Most women feel changes — better sleep, steadier energy, faster recovery — within the first 2–4 weeks. Skin hydration usually shifts by week 4–6. Visible elasticity and wrinkle changes are typically a 90-day story. Cellular renewal compounds, so most subscribers stay on indefinitely.

  • Can I cancel my subscription anytime?

    Yes. One click from your account dashboard, no phone call, no save-offer maze. You can also skip a month, swap delivery dates, or pause for travel. We'd rather you stay because it's working — not because it's hard to leave.

  • How does it taste?

    Coconut-pineapple, naturally flavored from real fruit. There is zero added sugar and no artificial sweeteners — so the flavor is light and refreshing, not syrupy. Mix in 8 oz of cold water (heat damages collagen peptides). Most people describe it as "a tropical sip" rather than a supplement.

  • Is it safe to take with medications?

    Bomi365 is made from food-grade ingredients used widely in the wellness category. That said, NR, CoQ10, and Resveratrol can interact with certain prescriptions (notably blood thinners, blood pressure medications, and chemotherapy regimens). If you take a daily prescription medication or are pregnant/nursing, please review the label with your physician before starting.

  • What's the science behind Cell-First collagen?

    Collagen synthesis depends on energy (ATP), cofactors (NAD+, vitamin C, glycine), and intact cellular signaling. As we age, mitochondrial function declines, NAD+ drops by ~50% by midlife, and oxidative stress damages newly produced collagen. Bomi365's formula targets each of those failure points alongside the peptides themselves — so the cells producing collagen actually have what they need to do the job.

  • Is it tested for purity and safety?

    Yes. Bomi365 is manufactured in an NSF-certified, cGMP-compliant facility in the United States and 3rd-party tested for heavy metals, microbiologicals, and label accuracy. Certificates of Analysis are available on request.