Cell-First Longevity Science

Hydrolyzed for superior absorption, these peptides help restore skin elasticity, boost hydration, and support bone and joint health. In a 12-week placebo-controlled clinical trial, collagen supplementation reduced wrinkles by 35% and improved skin elasticity, radiance, and overall appearance (Evans et al., 2020).

Often called the ultimate skin defender, vitamin C helps your body build and stabilize collagen for firm, youthful skin. Oral supplementation has been shown to raise skin vitamin C levels and strengthen the skin’s natural defense against UV and pollution-related damage. (Pullar et al., 2017).

Known as a “collagen multiplier,” glycine boosts fibroblast activity to enhance collagen production, strengthen skin, and accelerate repair. In human skin cell studies, glycine and its derivative glycinamide increased type I and III collagen, and when paired with vitamin C, boosted collagen production by over 150%, highlighting powerful synergy for skin renewal and resilience. (Lee et al., 2022). It also acts as a calming amino acid that supports deeper, more restful sleep (Bannai et al., 2012).

An advanced form of Vitamin B3 that helps replenish declining NAD⁺ levels to restore cellular energy, support mitochondrial function, and promote DNA repair. Human studies show NR supplementation can raise NAD⁺ by up to 60 percent within just 2 to 3 weeks, helping power healthy aging and cellular vitality (Trammell et al., 2016).

Also known as betaine, TMG is a natural nutrient that provides essential methyl groups to keep repair and recycling pathways working efficiently. By supporting NAD⁺ recycling and lowering homocysteine, TMG promotes cardiovascular and neurological health. Clinical studies have shown that TMG supplementation can reduce homocysteine levels by 10 to 20 percent (Craig, 2004).

Often called a longevity antioxidant, resveratrol helps activate the SIRT1 healthy aging pathway, supports DNA repair, and calms inflammation. Research shows it improves how cells produce energy and protects them from oxidative stress. In animal studies, resveratrol supported health and survival in mice fed a high-fat diet, and human trials have linked it to improvements in metabolic and vascular health (Baur et al., 2006).

Essential for energy and antioxidant defense, CoQ10 powers mitochondrial function while protecting skin from oxidative stress. In a 12-week placebo-controlled clinical trial, supplementation significantly reduced wrinkles and improved skin smoothness, with additional benefits observed for firmness and elasticity (Žmitek et al., 2017).

Known as nature’s moisture magnet, HA can bind up to 1,000 times its weight in water, helping skin stay plump, hydrated, and smooth. In a 12-week placebo-controlled clinical trial, oral HA significantly reduced wrinkle depth and improved skin smoothness and suppleness (Hsu et al., 2017).

A medicinal plant prized for its calming and restorative properties. In a 6-week clinical trial, an oral supplement containing Centella asiatica extract improved skin elasticity and the visible appearance of stretch marks, supporting its role in skin repair and overall resilience (Park, 2021).